Angiotensinogen gene G-6A polymorphism influences idiopathic pulmonary fibrosis disease progression
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چکیده
منابع مشابه
Angiotensinogen gene G-6A polymorphism influences idiopathic pulmonary fibrosis disease progression.
Angiotensin II is a growth factor that plays a key role in the physiopathology of idiopathic pulmonary fibrosis (IPF). A nucleotide substitution of an adenine instead of a guanine (G-6A) in the proximal promoter region of angiotensinogen (AGT), the precursor of angiotensin II, has been associated with an increased gene transcription rate. In order to investigate whether the G-6A polymorphism of...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2008
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00015808